By incorporating serum albumin levels, reflecting nutritional status, and absolute lymphocyte counts, representing immune competence, PNI provides valuable insights into the host’s ability to mount an effective anti-tumor response and tolerate aggressive therapies.21 Low PNI values have been consistently associated with poor prognosis, including decreased survival and increased susceptibility to treatment-related complications, across various malignancies, including cervical cancer. The gene discussed is ALB; the disease is cervical carcinoma.