PTGS2 and Parkinson disease: Moreover, these results indicated that Galangin downregulated the levels of IL-1β, TNF-α, IL-6, SRC, and PTGS2 mRNA compared with those of PD model mice (p < 0.05 or p < 0.01), However, it did not affect ALB, CDK1, CDK2, ESR1, PARP1 (Figures 9A–K).