Previous research has reported that L. plantarum DP189 exerts a neuroprotective effect through an increase in the expression of nuclear factor erythroid 2-related factor (Nrf2) and its target genes: SOD and glutathione peroxidase (GPx) in a murine model of induction of parkinsonism induced with MPTP. The gene discussed is NFE2L2; the disease is Parkinsonism.