CD274 and neoplasm: Their findings demonstrated that PD-L1 expression in cfRNA was comparable to PD-L1 protein expression in tumor tissue, with a median OS of 15 months and a 3-year OS rate of 30 % (HR: 0.97; 95 % CI: 0.44–2.10; p = 0.93) in PD-L1 positive patients [70].