Human cancer stem cells (CSCs) are a known targets of EGCG for cancer prevention and treatment; the fact that EGCG prevents the transcription and translation of genes encoding for stemness markers such as CD44, CD133, Nanog, Oct4, and Sox2 suggests that it averts CSCs from self‐renewing in general (Fujiki et al. 2017). This evidence concerns the gene POU5F1 and cancer.