(2) conducted morphological and immunohistochemical analysis of 6 cases of CIC-NUTM1 rearranged sarcoma, and concluded that CIC-DUX4 fusion transcripts induced up-regulation of multiple tumor enhancer activator 3 (PEA3/ETV4/E1AF) family genes, which could express ETV4 and WT1. The gene discussed is ETV4; the disease is sarcoma.