HLA-DRB1 and myeloid sarcoma: Many MHC class II risk alleles are associated with MS (such as HLA-DRB1*15:01, HLA-DRB1*13:03, and HLA-DRB1*03:01), while MHC class I alleles may confer protective effects (such as HLA-A*02:01, HLA-B*44:02, and HLA-B*38:01) (Moutsianas et al., 2015).