In this study, patients with metabolic syndrome who had hypothyroidism and those who did not had significantly higher levels of bodymass index SBP, DBP, FBS, PPBS; triglycerides total cholesterol, very low-density lipoproteins, low-density lipoproteins malondialdehyde,insulin and HOMA-IR than controls (Figure 2 - see PDF). This evidence concerns the gene INS and hypothyroidism.