Unlikethe binding sites as determined in myeloid leukemia cell lines bychromatin immunoprecipitation of p53-R175H, p53-Y220C, p53-M237I,p53-R248Q, and p53-R273H mutants, the target sites of p53-WT and p53-R282Wwere significantly associated with putative G-quadruplex sequences(PQSs). The gene discussed is TP53; the disease is myeloid leukemia.