HEPACAM and myeloid sarcoma: Furthermore, emerging data hints at a possible role for EBV-infected B cells in driving MS neuroinflammation through several plausible mechanisms, including a direct role of CNS penetrant EBV infected B cells, dysregulated T and NK responses, and molecular mimicry for example between EBV nuclear antigen 1 (EBNA1) and the glial cell adhesion molecule (GlialCAM) [12,13].