A differential expression of pattern recognition receptors (PRR) involved in polymicrobial sepsis defense was found in the left ventricle after CLP with Tlr2 expression upregulated at 8 h and 24 h (Fig. 6 A), which seemed to be reversed after both BMMSC and ASC treatment during the first 8 h after CLP procedure (Fig. 6A). Here, TLR2 is linked to Sepsis.