A small molecule screen of FDA-approved drugs identifies fasudil, a broadly selective ROCK inhibitor, as a chemical that rescues ciliogenesis after knockdown or mutation of two known ciliopathy genes (IFT88 and RPGRIP1L) in different cellular disease models but not in TMEM67. Increased ciliogenesis due to ROCK inhibition is likely due to increased ciliary vesicle trafficking and associated rescue of ciliary-mediated Sonic Hedgehog signalling. Here, IFT88 is linked to ciliopathy.