By categorizing patients with leukemia into distinct subtypes based on the French-American-British (FAB) classification (Bennett et al., 1976), we noticed a significant upregulation of CD37 in M4 and M5 AML (Figure S1C), and patients exhibiting high CD37 expression displayed an unfavorable prognosis (Figures S1C and S1D). The gene discussed is CD37; the disease is acute myeloid leukemia.