In hematological malignancies, CD37 is upregulated in B cell non-Hodgkin’s lymphoma (B-NHL), B cell acute lymphoblastic leukemia (B-ALL), and chronic lymphocytic leukemia (CLL) (Deckert et al., 2013; Scarfò et al., 2018). The gene discussed is CD37; the disease is B-cell chronic lymphocytic leukemia.