Baicalin, an active ingredient in the traditional Chinese medicine Baicalein, decreases p53 activation by downregulating the suppressor of cytokine signaling 1 (an essential signal transduction regulator protein that is crucial for immune modulation, inflammation regulation, and immunity), which reduces SLC7A11 transcription and improved liver fibrosis [80]. This evidence concerns the gene SLC7A11 and Hepatic fibrosis.