TP53 and neoplasm: During the early stages of the tumor, using WES, WGS, RNA‐Seq, Sanger sequencing, q‐PCR, or IHC assays can detect mutations in GTF2I, Harvey Rat Sarcoma Virus Oncogene (HRAS), Neuroblastoma RAS Viral Oncogene Homolog (NRAS), and TP53 genes [203, 204].