Notably, although prolonged butyrate pretreatment did not reduce CAR T‐cell infiltration rates into the enterocyte layer, it effectively inhibited tumor cell targeting, reflected by the preservation of E‐cadherin and ZO‐1 expression, which was similar to the control IAC model without CAR T‐cell perfusion (Figure8; Figures S10 and S11, Supporting Information). Here, CDH1 is linked to neoplasm.