Similarly, NCX1, the predominant sodium‐calcium exchanger isoform in sensory neurons, plays a critical role in calcium homeostasis and has been implicated in neurological disorders such as Alzheimer's disease [27], amyotrophic lateral sclerosis [28], and hypoxic–ischemic encephalopathy [29]. This evidence concerns the gene SLC8A1 and early-onset autosomal dominant Alzheimer disease.