However, for CTEPH, the miRNA panel significantly outperformed NT-proBNP, both in distinguishing CTEPH from other PH (balanced accuracy of 0.58 versus 0.47, sensitivity of 0.46 versus 0.75, specificity of 0.708 versus 0.19, P<0.0001), and from PAH (balanced accuracy of 0.68 versus 0.51, sensitivity of 0.69 versus 0.57, specificity of 0.68 versus 0.46, P=0.003, Table 3). Here, NPPB is linked to chronic thromboembolic pulmonary hypertension.