However, there was no significant difference in the performance of the miRNA panel compared with NT-proBNP in classifying PH-LHD (AUC of 0.63 versus 0.59, P=0.56, Figure 5D; Table S4), or PH-Lung (AUC of 0.58 versus 0.47, P=0.14, Figure 5E; Table S4). Here, NPPB is linked to medical procedure.