PYY and steatosis: Aragonès et al. (2019) found that it could promote the secretion of Peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) in intestinal L cells through the activation of GPR41 and GPR43 to affect multiple tissues, including the pancreas and the brain. PYY can inhibit intestinal peristalsis, reduce appetite and increase satiety (Psichas et al., 2015); the main function of GLP-1 is to promote the proliferation of islet β cell, inhibit its apoptosis, protect hepatocytes from steatosis, and regulate blood glucose by improving insulin sensitivity (Ji and Guo, 2020).