PLSCR1 and hepatocellular carcinoma: While healthy human hepatocytes at baseline express a low level of PLSCR1 (Karlsson et al., 2021), they found that PLSCR1 levels were significantly higher in the plasma of chronic HBV carriers (CHB) compared to HCC patients and healthy controls, implying that CHB patients with lower PLSCR1 levels may be at higher risk of developing HCC (Yuan et al., 2015).