TP73 and neoplasm: Known for its dual role in tumor suppression and promotion, p73 is also critical in the development and differentiation of specific tissues and organs, such as neuronal differentiation, the development of the central nervous and olfactory systems, and is highly expressed in airway ciliated columnar cells and the myoepithelial and basal cells of the salivary gland (Rufini et al., 2011; Yang et al., 2000; Lee et al., 2007).