There were significant associations between COX-2 expression and high-grade EOCs (χ2 = 8.36676, df 1, p 0.0038) or type II sub-type carcinomas (HGSC) (χ2 = 6.68351, df 1, p 0.0097) but not with the other histological sub-type (χ2 = 9.55719, df 5, p 0.0888) or age (χ2 = 1.77445, df 5, p 0.87939). This evidence concerns the gene PTGS2 and carcinoma.