The results indicated that preoperative albumin (OR, 0.838; CI, 0.733–0.957; p = 0.009), mechanical ventilation time (OR, 1.173; CI, 1.005–1.369; p = 0.043), and duration of VAP broad-spectrum antibiotic therapy (OR, 1.112; CI, 1.019–1.213; p = 0.018) were independent risk factors for MDRO VAP (Table 3). This evidence concerns the gene ALB and ventilator-associated pneumonia.