KLK3 and Familial prostate cancer: After including the significantly associated variables from the univariate regression analysis into the multivariate regression analysis, the results showed that age (OR: 1.052, 95% CI: 1.022–1.084, p = 0.001), SII (OR: 1.001, 95% CI: 1.000–1.001, p = 0.013), uric acid (OR: 1.003, 95% CI: 1.000–1.006, p = 0.020), and PSA (OR: 1.034, 95% CI: 1.022–1.004, p < 0.001) are independent risk factors for prostate cancer.