Researchers found that miR-506-3p can specifically target the 3' UTR of YAP, leading to the downregulation of YAP along with its associated target genes, including cellular myelocytomatosis (c-Myc) and connective tissue growth factor (CTGF), thereby inhibiting proliferation in LC cells (78). The gene discussed is CCN2; the disease is laryngotracheoesophageal cleft.