PTCH1 and Wiskott-Aldrich syndrome: In addition, RT-PCR, FISH, and RNA sequencing failed to identify the presence of GLI1 gene rearrangements, MALAT1::GLI1 fusion, PTCH1::GLI1 fusion, or an EWSR1-CTBP1, recently identified in a patient with Wiskott-Aldrich syndrome (6, 8).