LEP and obesity due to melanocortin 4 receptor deficiency: Figure 6E categorizes the citations into research clusters such as “body mass index,” “leptin,” “physical exercise,” “airway hyperresponsiveness,” “epidemiology,” and “glucocorticoid receptor.” These clusters correspond to the epidemiological, lifestyle intervention, and treatment studies discussed previously, collectively depicting the trajectory and key research areas within the field of obesity-related asthma.