Diagnoses: Congenital heart disease, HIV, rheumatoid arthritis, scleroderma, systemic lupus erythematosusMedications: Prostacyclins, endothelin receptor antagonists, soluble guanylate cyclase stimulator, phosphodiesterase type 5 inhibitorsProcedures: Echocardiogram, electrocardiogram, cardiac catheterization, ventilation perfusion scanLabs: Alkaline phosphatase, alanine transaminase, Bilirubin, B‐type natriuretic peptide, BUN, carbon dioxide, calcium, chloride, creatinine (serum), glucose, HCT, human chorionic gonadotropin, platelets, potassium, sodium, thyrotropin. This evidence concerns the gene GPT and scleroderma.