TLR4 and colorectal carcinoma: Based on the results in Sect. Screening of CRC key genes and Network pharmacology screening YGS affects candidate monomers target genes and pathway results of CRC stem cell metastasis relapse, YGS affected CRC candidate monomer was Gomisin B; the target gene was TLR4, and the action pathway was the NF-κB signaling pathway for subsequent research.