Furthermore, USP7 is known to have several target proteins particularly those involved in IRF4 regulation; therefore, performing a transcriptomic analysis of immunogenic and tolerogenic DCs in the absence or presence of USP7 inhibitor may reveal new targets that play a crucial role in tolerogenic versus immunogenic DC function and cDC1/cDC2 differentiation in the context of autoimmunity. The gene discussed is IRF4; the disease is Autoimmunity.