Cases of NUP214::ABL1 are variably reported constituting ~1-6% of T-ALL cases depending on age group, frequently with a cortical immunophenotype and co-occur with dysregulation of TLX1 and TLX3 [9, 14, 16, 17, 41, 42]. The gene discussed is TLX1; the disease is acute lymphoblastic leukemia.