ETP-ALL cases also demonstrated alterations in HOXA13 and MED12 with ETV6 or ZFP36L2 gene fusions (42% of ETP-ALL cases, 12% of all cases) or HOXA9/10/11 deregulation driven by NUP98/NUP214/KMT2A/MLLT10 gene fusions (30% of ETP-ALL cases, 7% of all cases) [17]. Here, HOXA9 is linked to acute lymphoblastic leukemia.