For example, BCRP is a key transport protein, which is encoded by ABCG2 gene and participates in the special function of patients in drug transport.772 There is a common genetic polymorphism in the ABCG2 gene worldwide, the common ABCG2 mutations can affect the efficacy of cancer drug therapy and the occurrence of adverse drug reactions, leading to changes in drug reactions and disease risk. This evidence concerns the gene ABCG2 and cancer.