Moreover, high levels of HIF-2α transcripts were associated with decreased OS (HR = 1.23, P = 0.012) and PFS (HR = 1.19, P = 0.035) in serous ovarian cancer, even other types of ovarian cancers, based on the Kaplan–Meier plotter (www.kmplot.com) analysis (Supplementary Fig. S5G). The gene discussed is EPAS1; the disease is ovarian serous adenocarcinoma.