To our knowledge, there is no evidence that suggests that embryonic upregulation of the PI3K-AKT-mTOR pathway, which causes MCDs, is related to these cases, and in Type III FCDs, whether the congenital FCD occurs first or is a result of the neoplasia (Najm et al., 2018). Here, AKT1 is linked to Schmid metaphyseal chondrodysplasia.