We observed that both the expression of the migratory integrin VLA-4 and the fraction of VLA-4Hi cells was significantly increased amid IL-7–ALT CD8+ T cells arriving early in tumor compared with IL-2 ALT, though this difference subsided by the 48 hour sampling point (gMFI in Figure 4B, 3 hours and 48-hours **P < 0.01, CD8+ T cell VLA-4Hi % in Figure 4C). Here, CD8A is linked to neoplasm.