In both groups, endogenous CD8+ T cell populations in tumor declined (time course shown for CD4+ T cells in Figure 1C, CD8+ T cells in Figure 1D. 48-hour IL-7–ALT CD8+ T cells 31.24× fold-increase versus IL-2–ALT 4.14 × **P < 0.01, 72-hour IL-7–ALT CD8+ T cells 42.2 × versus IL-2–ALT 5.88 ×, **P < 0.01). This evidence concerns the gene CD8A and neoplasm.