ATP6V1B2 and obesity due to melanocortin 4 receptor deficiency: Moreover, genes involved in lysosomal biogenesis and phagocytosis including Atp6v1b2, Atp6v0d2, Lipa, and Lamp2 were also reported to be induced in the ATMs in obesity (Xu et al., 2013; Coats et al., 2017).