PMEL and neoplasm: In contrast, in the group receiving particlized tebentafusp, the number of CD3+ T cells and HLA-A*02–01-GP-100-positive cells steadily decreased and was completed by 18 h after the second radiation in the primary tumor (Fig. 5F: GP-100, H: CD3+ T-cell,: 10-Gy,: 20 Gy, c, e) and pulmonary metastasis (Fig. 5G: GP-100, I: CD3+ T-cell,: 10-Gy,: 20 Gy, c’,e’).