CIH induces gene expression involved in lipogenesis [95], CIH induces Lysyl oxidase (LOX) expression which is involved in extra-cellular matrix rigidity [96], it also induces oxidative stress and lipid peroxidation [97], mitochondrial dysfunction [98], and finally, CIH induces intestinal permeability and disrupts the gut–liver axis [99], which were all discussed earlier as causative mechanisms of MASLD. Here, LOX is linked to metabolic dysfunction-associated steatotic liver disease.