Some of the most affected genes were DEAF1, DGKQ, OMA1, and ATG101, all showing an upregulation of 9 log2(FC) > N. Enriched pathways were very similar to those observed in PD vs. CN; however, both comparisons only have 5 dysregulated genes in common: RPL18A, PPDPF, LCE1A, SNORD38B, and RNVU1-17. The gene discussed is LCE1A; the disease is Parkinson disease.