Thrombin receptor PAR4 was the only gene that was upregulated in ADD when compared to PD; however, the dysregulation was one of the largest observed in our comparisons: 28 log2(FC) > N. Pathway enrichment analysis of the DEGs in ADD highlighted dysregulation of synapses, proteolysis, and signaling pathways (Figure 4C). This evidence concerns the gene F2R and Parkinson disease.