Notably, specific TCR fragments (e.g., TRB V12–4, TRB V18, and TRB V7-9) were selectively amplified in oAT from MUO individuals, with TRBV12–4 and TRBV12–3 previously implicated in antigen-specific responses in type 1 diabetes [40,41]. This evidence concerns the gene THRB and type 1 diabetes mellitus.