CRP and chronic kidney disease: In agreement with these findings, Vinereanu et al. showed that in pre-dialysis CKD stages G3–G5, AOPPs were significantly associated with C-reactive protein (CRP), high-density lipoprotein (HDL) levels, glycated hemoglobin (HbA1c) and pulse wave velocity (PWV) values, thus suggesting that the measurement of AOPPs could be of use for CV risk assessment in pre-dialysis CKD [41].