Cardiac biomarkers such as troponins (cTnI and cTnT), creatine kinase MB (CK-MB), brain natriuretic peptide (BNP), and high-sensitivity C-reactive protein (hs-CRP) play a pivotal role in diagnosing acute coronary syndromes (ACS), heart failure, and other cardiovascular conditions [13]. This evidence concerns the gene MAP3K14 and acute coronary syndrome.