MACF1 and glioblastoma: The results showed that MACF1 depletion sensitizes GBM cells to radiation, affecting cell viability and migration, and decreases the expression of p-ribosomal protein S6 of the mTOR signaling pathway, suggesting that this combinatorial strategy would be promising for GBM therapy and also highlighting the important role of MACF1 in GBM therapy [36].