CASP9 and neoplasm: Interestingly, we observed significant changes in the mitochondrial membrane proteins Bcl-2 and Bax (Figure 3e,f) as well as markers of the apoptotic pathway, including cleaved caspase-9, cleaved caspase-3, and cytochrome c in Dalton’s Lymphoma Ascites (DLA) tumours, indicating varied activity of the drug under two different conditions.