CTF1 and malaria: In contrast to Lif and Ctf1, vaccination had only a moderate effect (p-value < 0.05) on the malaria-induced IL-6 mRNA levels in the liver on day 1 p.i. Surprisingly, however, vaccination induced a significant increase in the constitutive mRNA level of Il6ra, encoding the membrane-bound IL6Rα, which remained elevated until the peak of parasitaemia on day 8 p.i. (cf. Figure 8).