CP and malaria: Both the LP and CP, as well as the AP, eventually converged at the level of C3-convertase, and the C3 mRNA level also increased more rapidly in the liver of vaccinated mice on day 4 p.i. than in unvaccinated mice, i.e., vaccination accelerated the formation of C3, induced by primary infection with P. chabaudi blood-stage malaria, and its cleavage product C3b is known to opsonize malaria-infected erythrocytes and merozoites, respectively [51].