It is also notable that the vaccination response of Colec11 differed from that of both Fcna and Masp1, insofar as vaccination per se increased the constitutive expression of Colec11, and the initial transient decrease in the malaria-responsive expression was much lower in the liver of vaccinated mice than in unvaccinated mice (Figure 5B–D). Here, MASP1 is linked to malaria.