EZH2 and tuberous sclerosis: Miat, EZH2-associated lncRNA, and Rncr4 may contribute to the reduction in the severity of renal cystic disease in Tsc1KO mice; however, the functions of these lncRNAs need to be further examined to define their role in the regulation of cystogenesis in Tsc1KO mice and TSC renal cystic disease in general.