The final model included genes such as DBH, MX2, UCN, IL4I1, BIRC5, ENTPD2, RDH12, ADCY1, CMA1, and CCR4, with their coefficients shown in Figure 3C. These genes represent critical regulators of immune and metabolic processes in ccRCC, highlighting their roles in tumor progression and patient prognosis. This evidence concerns the gene CCR4 and nonpapillary renal cell carcinoma.