While there is new evidence supporting the involvement of TRPV1 activation by the vanilloid capsaicin and by the endocannabinoid AEA in regulating cancer cell growth and disease progression in other gynaecological cancers [60], similar studies in EC models suggest that although these agonists might induce apoptosis, an in vivo impact that is unlikely to be substantial in EC [59]. Here, TRPV1 is linked to cancer.