Fortunately, over 45 human genes are involved in ALS, including Cu/Zn superoxide dismutase 1 (SOD1), TAR DNA-binding protein 43 (TDP-43), Chromosome 9 Open Reading Frame 72 (C9orf72), and Fusion sarcoma (FUS) [111]. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.