FYN and breast carcinoma: Remarkably, expression of KDM4A, the most abundantly expressed gene among KDM4 demethylases in TNBC cell lines (Figure 3—figure supplement 2A) was enriched in TNBC compared to other breast cancer subtypes (Figure 3F) and was positively correlated with FYN expression in CCLE database, suggesting that KDM4 regulates FYN mRNA levels (Figure 3G).